| Team | Gms | Wins | Saves | Strikeouts | ERA |
|---|
| Berkshire Greylocks | 150 | Ryan Dempster
| 14 | Huston Street
| 16 | Ryan Dempster
| 173 | Ryan Dempster
| 3.63 |
|---|
| Brooklyn Dodgers | 157 | Ricky Nolasco
| 14 | Andrew Bailey
| 18 | Ricky Nolasco
| 230 | Ricky Nolasco
| 3.04 |
|---|
| Camelot Capitals | 148 | Zack Greinke
| 17 | Heath Bell
| 18 | Zack Greinke
| 256 | Zack Greinke
| 2.82 |
|---|
| Cortland Spiders | 155 | Cole Hamels
| 11 | Chris Perez
| 14 | Gio Gonzalez
| 189 | Cole Hamels
| 5.13 |
|---|
| Dublin Doppelgangers | 150 | Randy Wolf
| 19 | Brian Wilson
| 31 | Dan Haren
| 224 | Dan Haren
| 2.19 |
|---|
| Florida Gators | 148 | Tim Lincecum
| 19 | Joe Nathan
| 36 | Tim Lincecum
| 238 | Tim Lincecum
| 2.45 |
|---|
| Greenwich Yankees | 148 | Roy Halladay
| 20 | J.P. Howell
| 20 | Adam Wainwright
| 189 | Roy Halladay
| 3.39 |
|---|
| Hamilton Travelers | 148 | Livan Hernandez
| 16 | Rafael Soriano
| 32 | Yovani Gallardo
| 185 | Yovani Gallardo
| 4.23 |
|---|
| Jefferson City Fighting SeaBees | 148 | Felix Hernandez
| 19 | Jose Valverde
| 17 | Felix Hernandez
| 212 | Felix Hernandez
| 3.16 |
|---|
| Jupiter Manatees | 148 | Scott Feldman
| 13 | Mariano Rivera
Ramon Troncoso
| 13 | Javier Vazquez
| 224 | Javier Vazquez
| 2.59 |
|---|
| Libertyville Trojans | 148 | Kip Wells
| 9 | Fernando Rodney
| 12 | Kip Wells
| 104 | Craig Stammen
| 5.16 |
|---|
| Long Island Sound | 153 | Justin Verlander
| 11 | Francisco Rodriguez
| 25 | Justin Verlander
| 274 | Ted Lilly
| 4.53 |
|---|
| Morrison Mustangs | 150 | Chris Tillman
Fausto Carmona
| 6 | Tony Pena
| 14 | Luke Hochevar
| 122 | Luke Hochevar
| 5.63 |
|---|
| Mountaintop Lightning Bolts | 157 | Chris Carpenter
Josh Johnson
| 16 | Chad Qualls
| 20 | Josh Johnson
| 194 | Chris Carpenter
| 2.71 |
|---|
| Newton Knights | 148 | Brian Bannister
| 12 | Trevor Hoffman
| 26 | Andy Pettitte
| 137 | Brian Bannister
| 3.97 |
|---|
| Orleans Barons | 150 | Jered Weaver
| 9 | Mike Gonzalez
| 29 | Jered Weaver
| 139 | Jered Weaver
| 4.06 |
|---|
| Portsmouth Clippers | 148 | Johan Santana
| 9 | Brandon Lyon
| 24 | Doug Davis
| 123 | Doug Davis
| 4.22 |
|---|
| Racine River Rats | 148 | Carl Pavano
| 12 | Jason Frasor
| 25 | Gavin Floyd
| 153 | Gavin Floyd
| 3.78 |
|---|
| Santurce Crabbers | 162 | Jon Lester
| 17 | Michael Wuertz
| 25 | Jon Lester
| 217 | Jon Lester
| 3.00 |
|---|
| Sciotoville Big Red Machine | 148 | James Shields
| 14 | Jon Papelbon
| 35 | James Shields
| 161 | Matt Cain
| 3.56 |
|---|
| Seattle Rainiers | 148 | Chad Billingsley
| 15 | David Aardsma
| 34 | Chad Billingsley
| 161 | Clayton Richard
| 3.26 |
|---|
| Springfield Peanut Vendors | 150 | Ubaldo Jimenez
| 13 | Carlos Marmol
| 17 | Ubaldo Jimenez
| 186 | Ubaldo Jimenez
| 2.59 |
|---|
| West Portsmouth Wanna Bees | 153 | Brett Anderson
| 10 | Matt Thornton
| 13 | Brett Anderson
| 142 | Joel Pineiro
| 3.95 |
|---|
| Wilton Warriors | 153 | Josh Beckett
| 7 | Joakim Soria
| 19 | Josh Beckett
| 184 | Josh Beckett
| 3.71 |
|---|
